The Epidemiology of TST Change in Korea
- Conditions
- TuberculosisLatent Tuberculosis
- Registration Number
- NCT01850043
- Lead Sponsor
- Asan Medical Center
- Brief Summary
TST will be analyzed in young general population in Korea. Young adults undertake TST as CDC recommendation. Participants with chest radiograph showing active TB lesion are excluded from this study.
- Detailed Description
Enroll criteria
* A term of whole military conscripts per year in one Reserve Force Battalion
* Military conscripts gather from all around area in Korea randomly
* Each participant undertake a chest X-ray (CXR) and blood tests including human immunodeficiency virus (HIV) at the start of initiatory training.
Exclusion Criteria
* Chest X-ray suggesting active TB
* HIV positive in serology
Design
* After giving informed consent, all participants receive one-step TST following standard procedures.
* The largest transverse diameter of induration is measured 48-72hr after injection.
* The investigator and these trained nurses were blinded to the status of their demographic characteristics.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 5552
- Military Conscripts age 18-29 years old
- Chest X-ray suggests active TB
- Positive HIV in serology
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TST positivity TST rate Two days after tuberculin injection Investigators measure induration size of tuberculin skin test 48 after tuberculin injection.
- Secondary Outcome Measures
Name Time Method BCG scar rates The day of tuberculin injection
Trial Locations
- Locations (1)
The Korean Institute of Tuberculosis
🇰🇷Osong, Chungcheongbuk-Do, Korea, Republic of