Efficacy of Unilateral Spinal Anaesthesia using very low drugs and administering drug very slowly.

Recruiting

• Conditions: American Society of Anaesthesiology physical status Grade 1 and 2

• Registration Number: CTRI/2018/03/012819
• Lead Sponsor: Leena H Parate

Brief Summary

This is a prospective study to assess



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|This is a prospective study to assess Unilateral spinal anaesthesia with 6mg of 0.5% (Hyperbaric) bupivacaine and 90mcg of buprenorphine using low dose- slow injection technique in ASA Class 1,2 adults aged 18 years to 65 years undergoing unilateral lower limb surgeries.

The primary outcome is assessment of successful unilateral spinal anaesthesia with 1.2 ml (6mg) of 0.5% (Hyperbaric) Bupivacaine and 90 mcg Buprenorphine using low dose- slow flow technique.

The secondary outcome is to monitor fluctuation in cardiovascular parameters (Blood Pressure, Heart Rate) before and after block,To monitor post-operative micturition time,To notice episode of post-operative nausea and vomiting,Requirement of Atropine and ephedrine intra-operatively.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-11
• Last Update Posted: 2018-03-20

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

ASA grade 1,2 Lower limb surgeries.

Exclusion Criteria

Patients with Autonomic neuropathy Patients with urinary catheter in situ Patients with Vascular pathology Patient on Anticoagulant Patients with Scoliosis Patients with history of Spinal surgeries Pregnancy Severe obese patient (BMI>35Kg/m2).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of Unilateral spinal anaesthesia with 6mg of 0.5% (Hyperbaric) bupivacaine and 90mcg of buprenorphin.	20 minutes after spinal anaesthesia

Secondary Outcome Measures

Name	Time	Method
To monitor fluctuation in cardiovascular parameters (Blood Pressure, Heart Rate) before and after block, Monitor post-operative micturition time, Notice episode of post-operative nausea and vomiting, Requirement of Atropine and ephedrine intra-operatively.

Trial Locations

Locations (1)

M.S.Ramaiah Hospital; 🇮🇳 Bangalore, KARNATAKA, India

M.S.Ramaiah Hospital

🇮🇳Bangalore, KARNATAKA, India

Dr Rahul Singh

Principal investigator

9953333899

drrahulsingh@outlook.com