A trial to assess which method of delivering local anaesthetic in to the abdominal wall provides the best pain relief after major gynaecological cancer surgery.

Not Applicable

• Conditions: Postoperative pain; Gynaecological cancer; Anaesthesiology - Anaesthetics; Cancer - Ovarian and primary peritoneal; Cancer - Womb (Uterine or endometrial cancer)

• Registration Number: ACTRN12612000981820
• Lead Sponsor: Mater Health Services

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-09-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

Women who are undergoing a laparotomy for gynaecological oncology procedures with an expected midline incision.

Exclusion Criteria

Conditions associated with opioid tolerance: regular opioid analgesia use in the last three months, previous IVDU
Abdominal wall block technically difficult to perform: eg obesity (BMI > 35)
Contraindication to abdominal wall block: local sepsis, local anaesthetic allergy, abnormal anatomy (for example nephrectomy scars)
Preference for other technique for postoperative analgesia, such as epidural infusion.
Presence of stoma
Age less than 18.
Inadequate capacity to consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the total average 24 to 48 hour post surgical morphine usage between the three groups (transverse abdominis plane (TAP) catheter group, posterior rectus sheath (PRS) catheter group and subcutaneous catheter group).[measured at 24 and 48 hours post surgery]

Secondary Outcome Measures

Name	Time	Method
VAS pain scores at rest and movement[24 and 48 hours post surgery];Peak flow measurements (hand held peak flow meter, best of three)[24 and 48 hours];Nausea and vomiting scores (VAS - 0-10cm line)[24 and 48 hours];average sedation scores (0-3 nurse assessed)[0-24 and 24-48 hours post surgery];Patient satisfaction scores : 3 question VAS scale (How would you rate your satisfaction with the pain relief? If you needed another operation will you request the same analgesia again? Would you recommend this type of analgesia to a friend?)[at 24 and 48 hours]