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Clinical Trials/NCT05843981
NCT05843981
Not Yet Recruiting
N/A

The Use of an Innovative, Thickened and Lasting Implant Comparing KS Versus TS Implants for Prosthetic Rehabilitations

Università degli Studi di Sassari1 site in 1 country42 target enrollmentMarch 1, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Dental Implant
Sponsor
Università degli Studi di Sassari
Enrollment
42
Locations
1
Primary Endpoint
Number of complications
Status
Not Yet Recruiting
Last Updated
2 years ago

Overview

Brief Summary

To compare the clinical and radiographic outcomes of two different implant systems with different implant-abutment connection: Osstem TS III (control group) versus Osstem KS (study group).

Registry
clinicaltrials.gov
Start Date
March 1, 2024
End Date
January 31, 2028
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Università degli Studi di Sassari
Responsible Party
Principal Investigator
Principal Investigator

Marco Tallarico

Assistant professor

Università degli Studi di Sassari

Eligibility Criteria

Inclusion Criteria

  • Any partially edentulous patient with partial edentulism, requiring at least two dental implant-supported rehabilitations, being 18 years or older, and able to sign an informed consent. Implant sites must allow the placement of two implants of at least 4 (premolars) or 4.5 (molars) mm of diameter and 8.5 mm of length. Smokers will be included and categorized into: 1) non smokers; 2) moderate smokers (smoking up to 10 cigarettes/day); 3) heavy smokers (smoking more than 11 cigarettes/day). In case of post-extractive sites, they must have been healing for at least 3 months before being treated in the study. Implants can be adjacent.

Exclusion Criteria

  • General contraindications to implant surgery.
  • Patients irradiated in the head and neck area.
  • Immunosuppressed or immunocompromised patients.
  • Patients treated or under treatment with intravenous amino-bisphosphonates.
  • Patients with untreated periodontitis.
  • Patients with poor oral hygiene and motivation.
  • Previous guided bone reconstruction at the intended implant sites.
  • Uncontrolled diabetes.
  • Pregnancy or nursing.
  • Substance abuser.

Outcomes

Primary Outcomes

Number of complications

Time Frame: Up to 5 years

Technical (fracture of the framework and/or the veneering material, screw loosening, etc.) and/or biologic (pain, swelling, suppuration, peri-implantitis, etc.) complications will be considered.

Number of Participants with implant failure

Time Frame: Up to 5 years

Defined as implant mobility and/or any infection dictating implant removal, and/or implant fracture and/or any other mechanical complication rendering the implant unusable. The stability of each individual implant will be measured by the local blinded outcome assessors manually tightening the screws with a torque of 30 Ncm at abutment connection at initial loading. At 1,3 and 5 years after loading, individual implants will be manually tested for stability. Once the single crowns will be screwed, their stability will be assessed by rocking the crown with the handles of two dental instruments.

Number of Participants with prosthesis failure

Time Frame: Up to 5 years

Whether it will not be possible to place the prosthesis because of implant failure or a prosthesis that has to be remade for any reason.

Secondary Outcomes

  • Rate of peri-implant marginal bone level changes(At 1,3 and 5 years)
  • Valuation of patient satisfaction(At 1,3 and 5 years)

Study Sites (1)

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