China STEMI Care Project Phase 2
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 18,000
- Locations
- 1
- Primary Endpoint
- Usage of both DAPT, statin, β blocker and ACEI/ARB in patients without contraindication
Study Overview
Brief Summary
The program is to improve STEMI medical care quality in China. With the documents issued by National Health and Family Planning Commission of the People's Republic of China, the program was initialed in at least 200 primary PCI capable hospitals together with hundreds of adjacent non-primary PCI capable hospitals in 15 provinces. STEMI patients with symptom onset within 30 days will be enrolled in 3 periods. In each period with 6-month interval, 30 patients will be enrolled consecutively from each PCI-capable center initially and from non-primary PCI capable hospitals later, thus at least 18,000 STEMI patients from primary PCI capable hospitals will be enrolled and all of them will be followed up for 1 year. Key performance indicators (KPIs) in STEMI care will be collected using both national PCI online registry and a program STEMI online registry database for the purpose of improvement of medical care. Hospital KPIs rank report and problem-based resolution will be feedback to each hospital after data analysis in each period. Comparison of every two cross-sectional data (self) and within one cross-sectional (inter-hospital) data will be used to evaluate the improvement of medical quality.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •STEMI patients with symptom onset within 30 days
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Usage of both DAPT, statin, β blocker and ACEI/ARB in patients without contraindication
Time Frame: 3 yeras
DAPT means dual antiplatelet therapy
Hospital admission via ambulance ratio
Time Frame: 2 years
Bypass ED ratio in patients with symptom onset within 12 hours
Time Frame: 12 hours
Door-to-ballnoon time in patients with symptom onset within 12 hours
Time Frame: 12 hours
Door-to-ballnoon time is the key index to evaluate treatment of primary PCI
Door-to-needle time in patients with symptom onset within 12 hours
Time Frame: 12 hours
Door-to-needle time is the key index to evaluate treatment of thrombolysis
Symptom onset to arrive in hospital
Time Frame: 2 years
1-year on time follow-up ratio
Time Frame: 1 year
In-hospital morbidity
Time Frame: 2 yeras
Referfusion ratio in patients with symptom onset within 12 hours
Time Frame: 12 hours
Referfusion including primary PCI and thrombolysis is the key strategy in STEMI care
Secondary Outcomes
No secondary outcomes reported
Investigators
Yong Huo
Director, Department of Cardiology
Peking University First Hospital