TO COMPARE FRACTIONATED WITH SINGLE DOSE OF SPINAL ANAESTHESIA IN PATIENTS UNDERGOING LOWER LIMB ORTHOPAEDIC SURGERIES

Not yet recruiting

Brief Summary: This study is a comparative randomised double blind study of fractionated with bolus dose of 0.5% hyperbaric bupivacaine with 25 mcgs Fentanyl in spinal anaesthesia for patients undergoing lower limb orthopaedic surgeries. The objective of the study is to compare the haemodynamic changes at different time intervals , onset and duration of sensory and motor block , duration of analgesia till the first request for rescue analgesics and side effects seen among the two groups . Total 60 patients will be randomly selected which belongs to ASA I-III . 60 patients will be divided into two groups 30 in each group by using sealed envelope technique . One group will recieve drug as bolus and other will recieve drug in fractionated manner. The drug will be given to all patients using 25 G Quincke’s spinal needle in sitting position.

Recruitment & Eligibility

Inclusion Criteria

Physical status I-III according to American Society of Anesthesiologists 2) Willing for spinal anaesthesia 3) Patients undergoing lower limb orthopaedic surgeries 4) BMI less than 35.

Exclusion Criteria

1. Absolute contraindications of spinal anaesthesia such as localized infection at injection site, patient’s inability to position during the procedure , patient’s refusal, allergy to anaesthetic drugs, increased intracranial pressure 2) Relative contraindication to spinal anaesthesia such as myelopathy or peripheral neuropathy, spinal stenosis, history of spinal surgery, spinal deformities, multiple sclerosis, spina bifida, aortic stenosis , altered mental status & coagulopathies.
1. BMI equal to or more than 35 4) Ineffective block with conversion to general anaesthesia.

Primary Outcome Measures

Name	Time	Method
Haemodynamic changes [Mean Arterial Pressure (MAP), Non Invasive Blood Pressure	The heart rate and blood pressure will be monitored at base line, just before subarachnoid block then at 5,10,15,20,40,60,80,100,120 mins and thereafter every \| 20 mins till the duration of surgery after giving spinal anaesthesia.
(NIBP) & Heart Rate (HR)] at different time intervals.	The heart rate and blood pressure will be monitored at base line, just before subarachnoid block then at 5,10,15,20,40,60,80,100,120 mins and thereafter every \| 20 mins till the duration of surgery after giving spinal anaesthesia.

Secondary Outcome Measures

Name	Time	Method
1)Onset and duration of sensory and motor block using pinprick test and modified Bromage scale	2)Duration of analgesia till the first request for rescue analgesic using VAS pain score

Locations (1): SGT HOSPITAL
🇮🇳
Gurgaon, HARYANA, India
SGT HOSPITAL
🇮🇳Gurgaon, HARYANA, India
Dr Sakshi Dhingra
Principal investigator
9711355379
dhingrasakshi2@gmail.com