The Role of Point-of-care Polymerase Chain Reaction in Managing Nosocomial Pneumonia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Nosocomial Pneumonia
- Sponsor
- Universitatea de Medicina si Farmacie Iuliu Hatieganu
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- To determine the sensibility and specificity of the device GeneXpert in diagnosis of pneumonia
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The study compares a device that is used for the detection of bacteria and MDR pathogens from skin, soft tissue and nose with the gold-standard (microbiological lab). It is a novel use for this device because it has been used in samples from the lower-respiratory tract.
Detailed Description
The purpose of this study is to find out if a POC-PCR device can be use in the diagnosis of hospital acquired pneumonia and ventilation-associated pneumonia.
Investigators
Balan Andrei Mihai
MD, Phd student
Universitatea de Medicina si Farmacie Iuliu Hatieganu
Eligibility Criteria
Inclusion Criteria
- •patients that are admitted for at least 48 hours
- •radiological findings typical for pneumonia
- •signs of infection
Exclusion Criteria
- •patient or patient relatives doesn't accept to enter the study
Outcomes
Primary Outcomes
To determine the sensibility and specificity of the device GeneXpert in diagnosis of pneumonia
Time Frame: 4 years
Comparison between device and gold standard
Utility of POC-PCR in managing pneumonia
Time Frame: 4 years
Decision making in pneumonia management