Nebulized Lidocaine Versus Placebo to Prevent Cough at Emergence From Anesthesia: a Double Blind Prospective Randomised Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- incidence of cough at emergence from general anesthesia
研究概览
简要总结
our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.
详细描述
our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.
This randomized controlled study will compare the effect of Lidocaine and placebo nebulization in the immediate pre operative period in order to evaluate the effectiveness in reducing post extubation cough and sore throat.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
盲法说明
The investigator will provide to the anesthesiologist 1 seringue containing either lidocaine or normal saline to be nebulized before induction of general anesthesia
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age>18 years
- •ASA status I or II
排除标准
- •Unexpected difficult laryngoscopy
- •Surgery>3 hours
研究组 & 干预措施
lidocaine group
the patients of this group will recieve nebulization of 5 ml of 2% lidocaine prior to induction of general anesthesia
干预措施: Lidocaine 2% (Drug)
Placebo group
the patients of this group will recieve nebulization of 5 ml of normal saline prior to induction of general anesthesia
干预措施: Normal saline (Drug)
结局指标
主要结局
incidence of cough at emergence from general anesthesia
时间窗: 30 minutes after the end of surgery
evaluation of incidence of cough at emergence from general anesthesia
次要结局
- incidence of sore throat(24 hours after tracheal extubation)
研究者
Mhamed Sami Mebazaa
professor
Mongi Slim Hospital