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Clinical Trials/NCT00105248
NCT00105248
Completed
Not Applicable

Multidimensional Intervention Program to Reduce Antibiotic Prescriptions for Acute Respiratory Tract Infections in Adults: a Randomized Controlled Trial in Primary Care

University Hospital, Basel, Switzerland1 site in 1 country900 target enrollmentJanuary 2004

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Tract Infections
Sponsor
University Hospital, Basel, Switzerland
Enrollment
900
Locations
1
Primary Endpoint
Up-take of antibiotic prescription confirmed by pharmacists within 2 weeks following the initial consultation
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the effectiveness of a short training program for general practitioners in patient-centered communication to reduce antibiotic prescription for acute respiratory tract infections (ARTI).

Detailed Description

Acute respiratory tract infections (ARTI) constitute the most frequent reason for seeking ambulatory care and for the prescription of antibiotics, despite the mostly viral origin of ARTI. Antibiotic prescriptions for ARTI increase unnecessary drug expenditures and are the main reason for increasing drug resistance of common bacteria. Evidence from intervention studies shows that merely providing physicians with guidelines and educational material for the management of acute respiratory tract infections is not enough to reduce antibiotic prescriptions for these conditions. The main reasons for antibiotic prescription in ARTI are non-medical and related to the physician patient relationship, patients' expectations and beliefs about the benefit of antibiotics. Therefore patient-centered communication could be a promising approach to reduce the rate of antibiotic prescription in ambulatory care. Comparison: General practitioners (GPs) trained in patient-centered communication in addition to evidence-based guidelines for diagnosis and treatment of ARTI compared to GPs just introduced to evidence-based guidelines.

Registry
clinicaltrials.gov
Start Date
January 2004
End Date
June 2004
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Basel, Switzerland
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 years or older
  • Symptoms of an acute respiratory tract infection for \>1 and \<28 days

Exclusion Criteria

  • Patients without informed consent
  • Not fluent in German
  • Patients with a psychiatric disorder
  • Patients with a recurrent respiratory system infection with antibiotic treatment in the previous 4 weeks

Outcomes

Primary Outcomes

Up-take of antibiotic prescription confirmed by pharmacists within 2 weeks following the initial consultation

Secondary Outcomes

  • Patient satisfaction with consultation (on validated scale)
  • days off from work
  • patient enablement (on validated scale)
  • re-consultation rates
  • days with restriction from ARTI within 14 days initial consultation
  • side effects from medication

Study Sites (1)

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