DRKS00028572
Recruiting
未知
fMRI Techniques for Studying Neural Substrates of Expressive Agrammatism and Normal Language Production
Director of Division of Cognitive Clinical Sciences at RWTH University Clinic0 sites110 target enrollmentMay 6, 2022
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Agrammatism
- Sponsor
- Director of Division of Cognitive Clinical Sciences at RWTH University Clinic
- Enrollment
- 110
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •General: Age from 18 years; German as first language; Right\-handedness (using the Edinburgh Handedness Inventory).
- •For patients: Broca's aphasia with agrammatic speech production and the ability to use at least two\-word utterances (aphasia and its severity are classified using the Aachen Aphasia Test (AAT); Etiology: stroke.
Exclusion Criteria
- •For healthy subjects only: confounding neurological disease (e.g., history of traumatic brain injury), dementia, or cognitive impairment the degree of which interferes with participation in the study.
- •For patients: other neurological diseases and disorders (e.g. neurocognitive disorder due to dementia).
- •General: Other basic physical illnesses that interfere with the examination due to their type and severity or have an impact on the parameters to be examined; Mental or behavioral disorder that may interfere with the investigation or acute suicidality; Drug, alcohol, or painkiller abuse; Pregnancy; Presence of electromagnetically influenced or metal\-containing medical devices in or in constant connection with the body (e.g. pacemakers, drug pumps, cochlear implants); Presence of metal parts in the body (e.g. screws after a bone fracture, metal splinters, metal prostheses, non\-MR compatible vessel clips); a known seizure disorder (epilepsy); Heart and/or brain surgery; Hypersensitivity to TMS for Experiment 3 (will be ruled out during recruitment)
Outcomes
Primary Outcomes
Not specified
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