DRKS00028572招募中未知

fMRI Techniques for Studying Neural Substrates of Expressive Agrammatism and Normal Language Production

Director of Division of Cognitive Clinical Sciences at RWTH University Clinic0 个研究点目标入组 110 人开始时间: 2022年5月6日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•General: Age from 18 years; German as first language; Right-handedness (using the Edinburgh Handedness Inventory).
•For patients: Broca's aphasia with agrammatic speech production and the ability to use at least two-word utterances (aphasia and its severity are classified using the Aachen Aphasia Test (AAT); Etiology: stroke.

•For healthy subjects only: confounding neurological disease (e.g., history of traumatic brain injury), dementia, or cognitive impairment the degree of which interferes with participation in the study.
•For patients: other neurological diseases and disorders (e.g. neurocognitive disorder due to dementia).
•General: Other basic physical illnesses that interfere with the examination due to their type and severity or have an impact on the parameters to be examined; Mental or behavioral disorder that may interfere with the investigation or acute suicidality; Drug, alcohol, or painkiller abuse; Pregnancy; Presence of electromagnetically influenced or metal-containing medical devices in or in constant connection with the body (e.g. pacemakers, drug pumps, cochlear implants); Presence of metal parts in the body (e.g. screws after a bone fracture, metal splinters, metal prostheses, non-MR compatible vessel clips); a known seizure disorder (epilepsy); Heart and/or brain surgery; Hypersensitivity to TMS for Experiment 3 (will be ruled out during recruitment)

发起方

Director of Division of Cognitive Clinical Sciences at RWTH University Clinic