The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.

Completed

• Conditions: Respiratory Tract Infection; Children

• Registration Number: NCT00265187
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Sputum specimens will be obtained from children \< 2 years of age and processed by different mode for the HMPV, RSV, Pertussis, Influenza A, B, Parainfluenza 1,2,3, Adenovirus. Clinical and epidemiological data will also be obtained.

Detailed Description

The purpose of the study is to asses the various pathogens of bronchiolitis in children and its' clinical manifestations. Prospective study in 3 Medical centers in Northern Israel. Included will be about 200 infants and children \< 2 years hospitalized with bronchiolitis. From each child sputum specimen will be obtained and processed for HUMP - PCR, Pertussis - PCR, RSV - ELISA, DFA, PCR, Influenza A, B, Parainfluenza 1,2,3 - DFA, PCR, Adenovirus - DFA. Epidemiological data will be obtained for every child by structured questioner. Clinical data will be daily obtained by scoring system.

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2005-12-13
• Study First Submitted QC: 2005-12-13
• Study First Posted: 2005-12-14
• Primary Completion: 2006-03
• Study Completion: 2006-03
• Status Verified: 2006-08
• Last Update Submitted: 2013-01-02
• Last Update Posted: 2013-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Age 0-24 months, hospitalized children, -

Exclusion Criteria

Previous hospitalization, previous RSV immunization, immunocompromised patient, previous inclusion in this study, inclusion in another study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (3)

Maier Hospital; 🇮🇱 Haifa, Israel

Pediatric department A, HaEmek Medical Center; 🇮🇱 Afula, Israel

Pediatric Depart ment , Bnai Zion Hospital; 🇮🇱 Haifa, Israel