Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask

Not Applicable

• Conditions: Postoperative Sore Throat
• Interventions: Other: Mouthwash; Other: chewed mint gum

• Registration Number: NCT04644900
• Lead Sponsor: Fudan University

Brief Summary

Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a streamlined liner of the pharyngeal airway (SLIPA).

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-11
• Study First Submitted: 2020-11-22
• Study First Submitted QC: 2020-11-22
• Last Update Submitted: 2020-11-22
• Study First Posted: 2020-11-25
• Last Update Posted: 2020-11-25
• Study Start: 2020-12-31
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

American Society of Anaesthesiologists(ASA)class I or II 20~65 years body mass index(BMI)scores<30 undergoing elective hysteroscopic surgery

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Exclusion Criteria

chronic laryngitis chronic bronchitis asthma gastroesophageal reflux allergies to study drugs recent use of non-steroidal anti-inflammatory drugs(NSAIDS) a history of upper respiratory tract infection in the past one week Mallampati grade>2 a history of steroid therapy.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
the Mouthwash group	Mouthwash	Patients in the mouthwash group received 15 ml of honeysuckle antibacterial mouthwash and vomited it out after 2 minutes
the gum group	chewed mint gum	patients in group gum chewed one piece of herbal sugar-free gum for 2 minutes and then spat it out.

Primary Outcome Measures

Name	Time	Method
the incidence of POST scores>3	within 24 hours after surgery.	POST was evaluated by the Numerical Rating Scale(NRS),which ranges from 0 to 10 points,with 0 indicating completely painless,1\~3 indicating mild discomfort,4\~6 indicating moderate pain,and 7\~10 indicating severe pain .

Secondary Outcome Measures

Name	Time	Method
the POST scores	2 hours,6 hours and 24 hours after surgery.	POST was evaluated by the Numerical Rating Scale(NRS),which ranges from 0 to 10 points,with 0 indicating completely painless,1\~3 indicating mild discomfort,4\~6 indicating moderate pain,and 7\~10 indicating severe pain .

Trial Locations

Locations (1)

Ethics Committee of The Obstetrics and Gynecology Hospital, Fudan University,; 🇨🇳 Shanghai, China