Controlled trial of comparison of the effect of controlled ovarian stimulation protocols on gene expression of germinal vesicle oocytes in infertile wome

Not Applicable

• Conditions: Contrlled Ovarian Stimulation protocols.; Female infertility

• Registration Number: IRCT2014031112307N3
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

age 18-40 years; normal serum level of steroidal hormones; male infertility, tubal factor infertility and unexplained infertility.
Exclusion criteria: genetic diseases; moderate or severe endometriosis and poly cystic ovarian.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of the effect of controlled ovarian stimulation protocols on gene expression of germinal vesicle oocytes in infertile women. Timepoint: ?End of sampling. Method of measurement: Real Time PCR.

Secondary Outcome Measures

Name	Time	Method
Determination of the effect of controlled ovarian stimulation protocols on adenosine triphosphatase 6 gene expression of human germinal vesicle oocytes. Timepoint: The end of sampling. Method of measurement: Real Time PCR.;Determination of the effect of controlled ovarian stimulation protocols on growth differentiation factor 9 gene expression of human germinal vesicle oocytes. Timepoint: The end of sampling. Method of measurement: Real Time PCR.;Determination of the effect of controlled ovarian stimulation protocols on bone morphogenetic protein15 gene expression of human germinal vesicle oocytes. Timepoint: The end of sampling. Method of measurement: Real Time PCR.;Determination of the effect of controlled ovarian stimulation protocols on neuronal apoptosis inhibitory protein gene expression of human germinal vesicle oocytes. Timepoint: The end of sampling. Method of measurement: Real Time PCR.