Protective ventilation during general anaesthesia for open abdominal surgery: a randomised controlled trial

Academic Medical Centre (AMC) (Netherlands)0 个研究点目标入组 900 人开始时间: 2010年12月6日最近更新: 2016年10月17日

适应症

试验速览

暂无简介。

•1. Aged less than 18 years
•2. Body mass index greater than 40 kg/m^2
•3. Laparoscopic surgery
•4. Previous lung surgery (any)
•5. Persistent haemodynamic instability, intractable shock (considered haemodynamic unsuitable for the study by the patient's managing physician)
•6. History of previous severe chronic obstructive pulmonary disease (COPD) (non-invasive ventilation and/or oxygen therapy at home, repeated systemic corticosteroid therapy for acute exacerbations of COPD)
•7. Recent immunosuppressive medication (patients receiving chemotherapy or radiation therapy within the last 2 months)
•8. Severe cardiac disease (New York Heart Association class III or IV, or acute coronary syndrome, or persistent ventricular tachyarrhythmia's)
•9. Mechanical ventilation greater than than 30 minutes (e.g., in cases of general anaesthesia because of surgery) within last 30 days
•10. Pregnancy (excluded by laboratory analysis)
•11. Acute lung injury or acute respiratory distress syndrome expected to require prolonged post-operative mechanical ventilation
•12. Neuromuscular disease (any)
•13. Consented for another interventional study or refusal to participate in the study

发起方

Academic Medical Centre (AMC) (Netherlands)