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临床试验/NCT06045676
NCT06045676尚未招募不适用

Electrocardiographic Changes Among Epileptic and Non Epileptic Seizures in Children at Sohag University Hospital

Sohag University1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2023年9月25日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
160
试验地点
1
主要终点
QT interval

研究概览

简要总结

Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures.

QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders.

Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
1 Year 至 12 Years(Child)
性别
All
接受健康志愿者

入选标准

  • children with drug resistant epilepsy.
  • febrile seizures.
  • age of 1 year to 12 years.

排除标准

  • age below 1 year and above 12 years
  • children with convulsion secondary cns infection , encephalitis, encephalopathy , toxic and metabolic problem

结局指标

主要结局

QT interval

时间窗: 12 months

Distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amany Khalaf Allah Elzanaty

Resident

Sohag University

研究点 (1)

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