Electrocardiographic Changes Among Epileptic and Non Epileptic Seizures in Children at Sohag University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- QT interval
研究概览
简要总结
Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures.
QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders.
Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 12 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children with drug resistant epilepsy.
- •febrile seizures.
- •age of 1 year to 12 years.
排除标准
- •age below 1 year and above 12 years
- •children with convulsion secondary cns infection , encephalitis, encephalopathy , toxic and metabolic problem
结局指标
主要结局
QT interval
时间窗: 12 months
Distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG
次要结局
未报告次要终点
研究者
Amany Khalaf Allah Elzanaty
Resident
Sohag University
