Relationship Between Muscle Mass Measured by Bioelectrical Impedance Analysis and Muscle Relaxation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 42
- 试验地点
- 2
- 主要终点
- ratio of result of first stimulus(T1) to result of supramaximal stimulation(T0)
研究概览
简要总结
Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of neuromuscular junction. The purpose of this study is to find relationship between muscle mass and muscle relaxation time.
详细描述
Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of neuromuscular junction. Until now, dose of rocuronium has been judged by patient's weight and height. However, height and weight do not represent exact muscle mass. The purpose of this study is to find relationship between muscle mass and muscle relaxation time. Measurement of muscle mass will be obtained using bioelectrical impedence analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 64 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •All patient who undergo general anesthesia.
- •Male; weight 70-75kg , height 170-175cm
- •Female; weight 53-58kg , height 158-163cm
排除标准
- •Liver and kidney disease
- •Any types of muscle disorder.
- •Metal materials or pacemaker in body
结局指标
主要结局
ratio of result of first stimulus(T1) to result of supramaximal stimulation(T0)
时间窗: two hours
T1 and T0 is obtained by train of four which is commonly used neuromuscular monitoring device.
次要结局
- completely suppression time of result of first stimulus(T1).(ten minutes)
研究者
Go Eun Bae
Clinical instructor
Korea University Anam Hospital