Association of Antibiotic Utilization Measures and Control of Extended-spectrum β-lactamases (ESBLs) in MICU1 and MICU2 at Buddhist Tzu Chi General Hospital.

Wyeth is now a wholly owned subsidiary of Pfizer0 个研究点目标入组 300 人开始时间: 2004年7月1日最近更新: 2009年9月9日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方
入组人数: 300
主要终点: For both MICU1 and MICU2 (acquisition), all culture results will be collected and recorded, then analyzed to determine the ESBL acquisition rate and bacterial isolates (E. coli or K. pneumoniae).

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

A single-center, prospective, comparative, antibiotic intervention study for patients admitted to MICU1 and MICU2

详细描述

To determine the value of using β-lactamases inhibitors in reducing the cases of ESBL producing E. coli or K. pneumoniae colonization and infection after 12 months.
To compare the acquisition rates of ESBL producing E. coli or K. pneumoniae at MICU1 and MICU2 after 12 months

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•All patients admitted or transferred to the ICU/burn units.
•Patients of either sex, 18 years of age or older.

排除标准

•Patient with hypersensitivity to penicillins, cephalosporins, and beta-lactamase inhibitors.

结局指标

主要结局

For both MICU1 and MICU2 (acquisition), all culture results will be collected and recorded, then analyzed to determine the ESBL acquisition rate and bacterial isolates (E. coli or K. pneumoniae).

次要结局

未报告次要终点

研究者

发起方

Wyeth is now a wholly owned subsidiary of Pfizer

申办方类型

Industry

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