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临床试验/CTRI/2023/10/058640
CTRI/2023/10/058640尚未招募Unknown

The effect of Pentoxifylline and Tocotrienol in endometrial rejuvenation in the case of thin endometrium opting for frozen embryo transfer

Indira IVF Hospital Private Limited0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
Unknown
状态
尚未招募
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • (a) History of one cancelled embryo transfer due to thin endo <7mm (after all conventional treatment as per institutional protocol.
  • (b) Age 25–45 years,
  • (c) Body mass index (BMI) 18.5 to 29.9 kg/m2
  • (d) Recipients of Donor oocyte & Donor embryo.

排除标准

  • (a) Presence of uncontrolled endocrine disorders (uncontrolled diabetes mellitus/ hyperprolactinemia, thyroid dysfunction,
  • (b) Previous major uterine surgery
  • (c) Previous hysteroscopic surgery
  • (d) Adenomyosis
  • (e) Endometriosis
  • (f) Untreated hydrosalpinx
  • (h) Cotreatment with any Nitric Oxide donor
  • (i) Patients with bleeding disorder or those who are at increased risk of retinal bleeding, peptic ulcer, or preoperative patients
  • (j) Patients with Renal Impairment: Patients with creatinine clearance less than 30 mL/min
  • (k) Allergy to xanthine derivatives, e.g., caffeine, theophylline, theobromine
  • (l) Acute myocardial infarction or severe coronary disease due to increased risk of myocardial demand
  • (m) Severe liver disease (Child pugh class C) or cirrhosis
  • (n) Pregnancy and Breastfeeding
  • (o) bleeding disorders (altered prothrombin time
  • (p) Co-administration with
  • (q) other antihypertensive drugs
  • (r) Glibenclamide or metformin
  • (s) other theophylline derivatives
  • (t) Co- treatment with Aspirin

研究者

发起方
Indira IVF Hospital Private Limited

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