Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic Valve Disease
- Sponsor
- Medical University of Vienna
- Enrollment
- 991
- Primary Endpoint
- Overall mortality
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under 50 year old patients.
Detailed Description
The purpose of this research project is to evaluate mortality (primary outcome) and incidence of heart attack, stroke, reoperation and first diagnosis of heart insufficiency, MACE (secondary outcomes) after aortic valve replacement in under 50 year olds. We aim to compare those outcomes between mechanical valves and bioprostheses. Data will be retrieved from the main social security carriers in Austria (covering 98% of its population) from 2010-2020.
Investigators
Hendrik Jan Ankersmit
Univ. Prof. , MD, MBA
Medical University of Vienna
Eligibility Criteria
Inclusion Criteria
- •isolated surgical aortic valve replacement in Austria
Exclusion Criteria
- •below 18 years of age
- •above 50 years of age
- •concomitant heart surgery
Outcomes
Primary Outcomes
Overall mortality
Time Frame: 10 years
all cause mortality after aortic valve replacement
Secondary Outcomes
- reoperation(10 years)
- stroke(10 years)
- heart insufficiency(10 years)
- heart attack(10 years)
- MACE(10 years)