Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 991
- 主要终点
- Overall mortality
研究概览
简要总结
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under 50 year old patients.
详细描述
The purpose of this research project is to evaluate mortality (primary outcome) and incidence of heart attack, stroke, reoperation and first diagnosis of heart insufficiency, MACE (secondary outcomes) after aortic valve replacement in under 50 year olds. We aim to compare those outcomes between mechanical valves and bioprostheses.
Data will be retrieved from the main social security carriers in Austria (covering 98% of its population) from 2010-2020.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •isolated surgical aortic valve replacement in Austria
排除标准
- •below 18 years of age
- •above 50 years of age
- •concomitant heart surgery
结局指标
主要结局
Overall mortality
时间窗: 10 years
all cause mortality after aortic valve replacement
次要结局
- reoperation(10 years)
- stroke(10 years)
- heart insufficiency(10 years)
- heart attack(10 years)
- MACE(10 years)
研究者
Hendrik Jan Ankersmit
Univ. Prof. , MD, MBA
Medical University of Vienna