Surgical Position Associated Intra-abdominal Pressure (IAP) changes in Neurosurgery : The SPAIN study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To estimate the change of Intraabdominal pressure (IAP) from the baseline in different neurosurgical positions intraoperatively
研究概览
简要总结
This is a prospective single center observational study , where Intra abdominal pressure changes will be ,monitored in different neurosurgical positions , like supine , prone, lateral and sitting . Secondary outcome will be to the impact of intraoperative IAP changes in post operative hepatic and renal function & on duration of ICU stay, hospital stay and neurological outcome ( using GOS ) . IAP will be measured using intravesical catheter technique Intraoperatively , and post operatively for 24 hour. Post operatively LFT and KFT will be done daily for 72 hours and renal injury status will be accessed using AKIN criteria.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult Patients of ASA I & II category (18 to 60 years of age) scheduled to undergo craniotomy for elective neurosurgical procedures.
排除标准
- •1 Emergency neurosurgical cases.
- •2 Patients with active abdominal pathology (eg: Liver disease and kidney disease, abdominal trauma etc) and/or preoperative hepatic or renal impairment.
- •3 Contraindication to bladder catheterisation (eg: bladder surgery, injury, urethral strictures etc) 4 Preoperative haemodynamic instability.
- •5 Pregnancy, Morbid obesity.
结局指标
主要结局
To estimate the change of Intraabdominal pressure (IAP) from the baseline in different neurosurgical positions intraoperatively
时间窗: O day and upto 3rd day
次要结局
- To study the impact of intra-operative IAP changes with post-operative hepatic and renal function.(From the day of surgery to 3 post operative days .)
- To study the impact of intra-operative IAP changes with ICU stay, hospital stay and the neurological outcome.(From the day of surgery till hospital discharge)