Angiography Derived Index of Microcirculatory Resistance in Patients With Acute Myocardial Infarction
- Conditions
- Acute Myocardial Infarction (AMI)
- Interventions
- Other: Angiography derived index of micro-circulatory resistance (Angio-IMR)
- Registration Number
- NCT05696379
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of acute myocardial infarction (AMI) patients, and has been shown to be associated with poor prognosis. Angiography derived index of micro-circulatory resistance (Angio-IMR) is a novel pressure-wire free approach to assess coronary microvascular disease with great diagnostic performance. The current study will further investigate the prognostic value of Angio-IMR in patients with AMI in multicenter retrospective cohort.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 5000
- Acute myocardial infarction patients who underwent successful percutaneous coronary intervention
- No appropriate coronary angiography images (inferior image quality, image loss, severe arteries overlap, or significant artifact)
- Previous coronary artery bypass graft
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description NSTEMI with low Angio-IMR Angiography derived index of micro-circulatory resistance (Angio-IMR) Patients with non-ST segment elevation myocardial infarction and low Angio-IMR STEMI with high Angio-IMR Angiography derived index of micro-circulatory resistance (Angio-IMR) Patients with ST segment elevation myocardial infarction and high Angio-IMR STEMI with low Angio-IMR Angiography derived index of micro-circulatory resistance (Angio-IMR) Patients with ST segment elevation myocardial infarction and low Angio-IMR NSTEMI with high Angio-IMR Angiography derived index of micro-circulatory resistance (Angio-IMR) Patients with non-ST segment elevation myocardial infarction and high Angio-IMR
- Primary Outcome Measures
Name Time Method Cardiac death or readmission for heart failure in 1 month 1 month Incidence of cardiac death or readmission for heart failure during first 1 month follow-up.
Cardiac death or readmission for heart failure in 6 months 6 month Incidence of cardiac death or readmission for heart failure during first 6 months follow-up.
Cardiac death or readmission for heart failure in 1 year 1 year Incidence of cardiac death or readmission for heart failure during first 1 year follow-up.
Cardiac death or readmission for heart failure in 2 years 2 year Incidence of cardiac death or readmission for heart failure during first 2 years follow-up.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Second Affiliated Hospital, School of Medicine, Zhejiang University
🇨🇳Hangzhou, Zhejiang, China