Comparative evaluation of Effectiveness of Bupivacaine Injection & Lidocaine Injection in Management of Patients with Myofascial Pain Syndrome – A randomized Controlled trial.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Pain pressure Threshold
研究概览
简要总结
Myofascial Pain Syndrome (MPS) is a common,chronic, and regional musculoskeletal condition. MPS are a large group ofmuscular disorders, such a syndrome is a disorder concerning the muscle, itsfascia or both and is accompanied by pain in an affected area or a zone ofreference and malfunction of the affected muscle. Management of MPS consists of invasive and non-invasivetreatment interventions, in conjunction with identification and removal ofperpetuating factors. Invasive procedures include dry needling of Muscle TriggerPoints (MTrPs) and injection with botulinum toxin or local anaesthetic agentssuch as lidocaine.Traditional approaches to treating MPS haveincluded like Physical Therapy like stretch and spray, massage, transcutaneouselectrical nerve stimulation, massage, local heat and medications such as Musclerelaxants , NSAIDS , Tricyclic agents which is considered as a muscle relaxantwith anti-inflammatory and analgesic effects . Amongst the different Treatment Modalities,According to different studies Trigger Point Therapy is considered to the Goldstandard. Trigger-point injection is indicated for patients whohave symptomatic active trigger points that produce a twitch response topressure and create a pattern of referred pain. In comparative studies, dryneedling was found to be as effective as injecting a solution such as lidocaineor Bupivacaine. However, post injection soreness resulting fromdry needling was found to be more intense and of longer duration than thesoreness experienced by patients injected with local anaesthetic. Notmuch studies have been done to compare two local anaesthetic agents in Triggerpoint therapy , therefore this study is being conducted to see theeffectiveness of a long acting local anaesthetic i.e Bupivacaine and a shorteracting local anaesthetic i.e Lignocaine .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients 18 to 60 years of age (either sex).
- •Patients will be selected according to Simons Criteria.
- •History of recurrent or chronic regional musculoskeletal pain in Cranio-facial caused by trigger points.
- •Pharmacologic washout of ≥72 hours for central analgesics, NSAIDs, and antidepressants Patients who have given Informed consent.
排除标准
- 未提供
结局指标
主要结局
Pain pressure Threshold
时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30
Intensity of Pain
时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30
Maximum Mouth Opening
时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30
次要结局
未报告次要终点
