跳至主要内容
临床试验/CTRI/2024/03/063616
CTRI/2024/03/063616尚未招募4 期

Comparative evaluation of Effectiveness of Bupivacaine Injection & Lidocaine Injection in Management of Patients with Myofascial Pain Syndrome – A randomized Controlled trial.

DR. SRISHTY SNEH1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2024年3月18日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
45
试验地点
1
主要终点
Pain pressure Threshold

研究概览

简要总结

Myofascial Pain Syndrome (MPS) is a common,chronic, and regional musculoskeletal condition. MPS are a large group ofmuscular disorders, such a syndrome is a disorder concerning the muscle, itsfascia or both and is accompanied by pain in an affected area or a zone ofreference and malfunction of the affected muscle. Management of MPS consists of invasive and non-invasivetreatment interventions, in conjunction with identification and removal ofperpetuating factors. Invasive procedures include dry needling of Muscle TriggerPoints (MTrPs) and injection with botulinum toxin or local anaesthetic agentssuch as lidocaine.Traditional approaches to treating MPS haveincluded like Physical Therapy like stretch and spray, massage, transcutaneouselectrical nerve stimulation, massage, local heat and medications such as Musclerelaxants , NSAIDS , Tricyclic agents which is considered as a muscle relaxantwith anti-inflammatory and analgesic effects . Amongst the different Treatment Modalities,According to different studies Trigger Point Therapy is considered to the Goldstandard. Trigger-point injection is indicated for patients whohave symptomatic active trigger points that produce a twitch response topressure and create a pattern of referred pain. In comparative studies, dryneedling was found to be as effective as injecting a solution such as lidocaineor Bupivacaine. However, post injection soreness resulting fromdry needling was found to be more intense and of longer duration than thesoreness experienced by patients injected with local anaesthetic. Notmuch studies have been done to compare two local anaesthetic agents in Triggerpoint therapy , therefore this study is being conducted to see theeffectiveness of a long acting local anaesthetic i.e Bupivacaine and a shorteracting local anaesthetic i.e Lignocaine .

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients 18 to 60 years of age (either sex).
  • Patients will be selected according to Simons Criteria.
  • History of recurrent or chronic regional musculoskeletal pain in Cranio-facial caused by trigger points.
  • Pharmacologic washout of ≥72 hours for central analgesics, NSAIDs, and antidepressants Patients who have given Informed consent.

排除标准

  • 未提供

结局指标

主要结局

Pain pressure Threshold

时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30

Intensity of Pain

时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30

Maximum Mouth Opening

时间窗: DAY 1 , DAY 5 , DAY 9 , DAY 15 , DAY 30

次要结局

未报告次要终点

研究者

发起方
DR. SRISHTY SNEH
申办方类型
Other [self]

研究点 (1)

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