Colposcopy and preterm birth study
Not Applicable
- Conditions
- Gynaecological HPV related diseases where patients have been referred to colposcopy.Urological and Genital DiseasesGynaecological HPV related diseases
- Registration Number
- ISRCTN10933736
- Lead Sponsor
- niversity of Helsinki and Helsinki University Hospital
- Brief Summary
2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29165793 population-based results for the association between loop electrosurgical excision and subsequent preterm delivery (added 11/04/2019) 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31176553 HPV type distribution results (added 11/06/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36153296/ (added 29/09/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- Female
- Target Recruitment
- 1279
Inclusion Criteria
1. Any woman 18 years of age or older
2. Referred to colposcopy at Helsinki University Hospital
Exclusion Criteria
Under the age of 18
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of preterm birth after colposcopy and/or cervical treatment is measured using the information in hospital records and national health registries at five, seven and ten years after enrollment.
- Secondary Outcome Measures
Name Time Method <br> 1. Prevalence, clearance, and incidence of new HPV infections is measured with the extra cervical brush samples (HPV genotyping) obtained at any visit at the colposcopy clinic up to two years after enrolment<br> 2. Sensitivity and specificity of colposcopic evaluation is measured using data from hospital records up to two years after enrolment<br> 3. Rate of complications of colposcopy and treatment and risk factors are measured using using data from hospital records up to two years after enrolment<br>