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Clinical Trials/NCT07267923
NCT07267923
Completed
Not Applicable

Investigation of the Acute Effects of Traditional and Functional Inspiratory Muscle Training on Muscle Oxygenation in Chronic Obstructive Pulmonary Disease

Saglik Bilimleri Universitesi2 sites in 1 country24 target enrollmentStarted: November 11, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
24
Locations
2
Primary Endpoint
Muscle oxygenation levels (SmO₂)

Overview

Brief Summary

This study aims to compare the effects of functional and conventional inspiratory muscle training (IMT) on post-exercise muscle deoxygenation in individuals with Chronic Obstructive Pulmonary Disease (COPD). Participants will complete both training modalities on separate days. A 2-minute walk test (2MWT) will be performed baseline, and after each session. Muscle oxygenation (SmO₂) will be assessed using near-infrared spectroscopy . Dyspnea and fatigue will be evaluated with the Modified Borg Scale, and heart rate and oxygen saturation (SpO₂) will be measured by pulse oximetry. Measurements will be recorded before, after training and at the end of the walking test.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Being 18 years of age or older,
  • Having a diagnosis of COPD,
  • Being in stage II-III according to the GOLD classification,
  • Being able to mobilize independently.

Exclusion Criteria

  • Having a recent exacerbation or complication requiring hospitalization,
  • Having had a respiratory tract infection within the past month,
  • Having any disease or medical condition that prevents participation in exercise, -Having cognitive impairment (a score of \<24 on the Mini-Mental Test).

Arms & Interventions

Chronic Obstructive Pulmonary Disease

Experimental

Intervention: Traditional inspiratory muscle training (Other)

Chronic Obstructive Pulmonary Disease

Experimental

Intervention: Functional inspiratory muscle training (IMT) (Other)

Outcomes

Primary Outcomes

Muscle oxygenation levels (SmO₂)

Time Frame: 1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT

Muscle oxygenation (SmO₂) will be assessed using near-infrared spectroscopy .

Secondary Outcomes

  • Fatigue(1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT)
  • Dyspnea(1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT)
  • Heart rate(1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT)
  • Saturation (SPO2)(1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT)
  • hemoglobin(1. day - baseline measurement-before and after 2MWT , 1. day- before and after IMT and after 2MWT 2. day- before and after FIMT and after 2MWT)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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