Patient-Centered Care for the Older Adult With Hematologic Malignancy

Not Applicable

Completed

• Conditions: Hematologic Malignancy
• Interventions: Other: Baseline Geriatric Screening/Assessment; Other: Geriatrician Co-Management

• Registration Number: NCT02359838
• Lead Sponsor: Dana-Farber Cancer Institute

Brief Summary

This research study is evaluating if co-management by a geriatrician embedded in the oncology clinic can improve outcomes for frail older adults with blood cancers. A rigorous pre-entry frailty assessment by a trained research assistant will be followed by randomization to geriatrician co-management versus usual care for patients found to be frail or pre-frail.

Detailed Description

Older adults have unique health concerns, and in particular, older adults with blood cancers may have different disease and other health related issues than younger adults with similar diagnoses. One aspect of aging which can make older adults more vulnerable is frailty. Frailty is a general term that describes a decline in multiple areas of health, including the loss of energy, physical ability, and mental ability. Frailty can make it difficult for patients with cancer to respond to treatment and more likely to have side effects. On the other hand, many older patients are not frail despite advanced age. This study is being done to determine if co-management by a geriatrician of older adults who are found to be frail through a detailed baseline assessment can improve outcomes.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2015-02-01
• Study First Submitted: 2015-02-02
• Study First Submitted QC: 2015-02-09
• Study First Posted: 2015-02-10
• Primary Completion: 2018-05-01
• Study Completion: 2020-05-01
• Status Verified: 2022-03
• Results First Submitted: 2022-03-24
• Results First Submitted QC: 2022-03-24
• Last Update Submitted: 2022-03-24
• Results First Posted: 2022-07-19
• Last Update Posted: 2022-07-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• All patients aged 75 and older who present for an initial consultation at the Dana-Farber/Brigham and Women's Cancer Center for hematologic malignancy (transplantation consultation excluded).
• Assessed to be pre-frail or frail on formal baseline geriatric assessment.

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Exclusion Criteria

• Not willing to participate

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Usual Care	Baseline Geriatric Screening/Assessment	Frail/pre-frail hematologic oncology patients receive usual care
Geriatrician Co-Management	Baseline Geriatric Screening/Assessment	Frail/pre-frail hematologic oncology patients receive co-management by a geriatrician
Geriatrician Co-Management	Geriatrician Co-Management	Frail/pre-frail hematologic oncology patients receive co-management by a geriatrician

Primary Outcome Measures

Name	Time	Method
Overall Survival	One year	Overall Survival at one year

Trial Locations

Locations (1)

Dana Farber Cancer Institute; 🇺🇸 Boston, Massachusetts, United States