Are alpha blockers effective in the treatment of bladder elimination problems in female patients with Multiple Sclerosis?

Phase 3

Recruiting

• Conditions: Bladder dysfunction in MS; bladder dysfunction in Multiple Sclerosis; 10012303; 10004994

• Registration Number: NL-OMON47090
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- Female
- Age >= 18 years
- Any form of MS
- Residual urine 60 ml - 250 ml
- Adequate understanding of the Dutch language

Exclusion Criteria

- Dependency of wheel chair
- Being bedridden
- Indwelling catheter
- Clean intermittent catheterization
- Acute attack of MS
- Current treatment with an alpha-blocker
- Pregnancy/breastfeeding
- Severe kidney dysfunction
- Orthostatic hypotension

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Residual urine, measured within 10 minutes after a voluntary void at t=0 and<br /><br>t=6 weeks.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Quality of life (questionnaire: Qualiveen) at t=0 and t=6 weeks.<br /><br>- Symptom scores of voiding complaints (questionnaires: UDI-6 and IIQ-7) at t=0<br /><br>and t=6 weeks.</p><br>