sing a test called QEEG i.e. quantitative electroencephalogram to check the response to clozapine in patients of schizophrenia with no response on multiple medications previously.
- Conditions
- Health Condition 1: F20- Schizophrenia
- Registration Number
- CTRI/2023/09/058046
- Lead Sponsor
- Government medical college and hospital sector 32
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Diagnosis of schizophrenia according to ICD-11.24
2. Established as Treatment resistant schizophrenia as per Treatment response and resistance
in psychosis (TRIPP) working group consensus guidelines3
3. Patients who have not received clozapine in the past.
1. Patients with co-morbid substance dependence (except nicotine and caffeine)
2. Patients with history of severe cardiac or renal disorders, or a history of neutropenia,
bone-marrow disorders, paralytic ileus, acute substance-induced psychosis or
intoxication, circulatory collapse or epilepsy.
3. Patients on any depot I/M drug preparation.
4. Patients who have received ECT in past 2 weeks.
5. Patients who are lactating or pregnant.
6. Patient with any neurological disorders.
7. Patients with history of seizure in past.
8. Patients on any immunosuppressant.
9. Acutely suicidal patients.
10. Acutely violent patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method