Efficacy of Low-glycemic Index Medical Food on Satiety

Phase 1

Completed

• Conditions: Obesity; Low glycemic index medical food; Gut hormone; Satiety

• Registration Number: TCTR20211111003
• Lead Sponsor: Thai Otsuka Pharmaceutical Co., Ltd

Brief Summary

Both normal weight and obese had significantly higher GLP-1 and PYY AUCs and significantly lower ghrelin AUCs after the LGI compared to SB, which were related to the satiety and hunger scores. After the LGI, both groups rated themselves as less hungry and fuller than SB. Moreover, Ghrelin AUC of obese was significantly lower than normal weight after consuming the LGI which was related to a significantly lower hunger score and a tendency to eat less lunch than after SB.

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-08-28
• Study Start: 2021-11-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Normal weight and obesity adults (10 males and 10 females per group) which classified by percentage of body fat.
2. Subjects who used not of medicine or weight loss supplements
3. Subjects who had no medical history of gastritis or use of antacid

Exclusion Criteria

Liver disease, kidney disease, thyroid disease, anemia and infectious disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified