CTRI/2024/11/077212Not yet recruitingPhase 2
A prospective randomised controlled comparative clinical study of attenuation of hemodynamic responses to endotracheal extubation using lignocaine and combination of lignocaine and diltiazem
Mysore medical college and research institute1 site in 1 country60 target enrollmentStarted: December 23, 2024Last updated:
Trial Snapshot
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Assess the hemodynamic responses to endotracheal extubation by monitoring heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure
Study Overview
Brief Summary
A comparative study to assess the stress response of the patient to endotracheal extubation using two different types of drugs
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA grade 1 and 2 patients Patients with modified mallampati scores 1 and 2 Patients posted for elective surgeries under general anaesthesia.
Exclusion Criteria
- •Patients with difficult airway Patients with coexisting cardiovascular diseases Patients with heart rate less than 60 beats per minute Patients with blood pressure less than 100/60 mmhg Patients with documented hepatic or renal diseases Pregnant patients.
Outcomes
Primary Outcomes
Assess the hemodynamic responses to endotracheal extubation by monitoring heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure
Time Frame: 10 minutes
Secondary Outcomes
- Assess the smoothness of extubation(10 minutes)
Investigators
Dr SEENIVASAN V
Mysore medical college and research institute
Study Sites (1)
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