LHC-CIDI-5 in Hong Kong

Recruiting

• Conditions: Major Depressive Episode (MDE); Major Depressive Disorder (MDD); Persistent Depressive Disorder (PDD); Suicidal Ideation; Suicidal Plan; Suicidal Attempt; Suicidal Gesture; Nonsuicidal Self-Injury; Manic Episode; Hypomanic

• Registration Number: NCT06804525
• Lead Sponsor: The University of Hong Kong

Brief Summary

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders.

To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study.

In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation.

This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-01
• Study Start: 2025-01-18
• Study First Submitted: 2025-01-24
• Study First Submitted QC: 2025-01-27
• Last Update Submitted: 2025-01-27
• Study First Posted: 2025-02-03
• Last Update Posted: 2025-02-03
• Primary Completion: 2026-09
• Study Completion: 2027-04

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• All household members aged 25 years old and over are randomly sampled from the Census and Statistics Department List of Quarters
• Live in the address sampled from the Census and Statistics Department List of Quarters
• Reside in Hong Kong for at least six months in the past year
• Able to read and communicate in Chinese or English
• Without linguistic or cognitive difficulties

Exclusion Criteria

• Domestic workers

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anger Attacks	Immediately following intervention or recruitment	The main outcome in this module is the lifetime prevalence of Intermittent Explosive Disorder (IED)
Depression	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Major Depressive Episode (MDE) and Major Depressive Disorder (MDD)
Persistent Depression	Immediately following intervention or recruitment	The main outcome in this module is the lifetime prevalence of Persistent Depressive Disorder (PDD)
Self Harm	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Suicidal Ideation, Suicidal Plan, Suicidal Attempt, Suicidal Gesture, and Nonsuicidal Self-Injury.
High Mood	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Manic Episode, Hypomanic, Bipolar I Disorder, Bipolar Sub Disorder, and Bipolar II Disorder
Worry and Anxiety	Immediately following intervention or recruitment	The main outcome in this module is the lifetime prevalence of Generalized Anxiety Disorder (GAD)
Panic Attacks	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Panic Attack and Panic Disorder.
Obsessions and Compulsions	Immediately following intervention or recruitment	The main outcome in this module is the lifetime prevalence of Obsessive-Compulsive Disorder (OCD)
Stressful Experiences	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Posttraumatic Stress Disorder (PTSD), PCL-SC PTSD, and PCL-5 PTSD.
Tobacco, Alcohol, and Drugs	Immediately following intervention or recruitment	The main outcomes in this module are the lifetime prevalence of Alcohol Use Disorder (AUD) and Substance Use Disorder (SUD)

Trial Locations

Locations (1)

The University of Hong Kong; 🇭🇰 Hong Kong, SAR, Hong Kong