Synovial immune alterations and biomarkers of arthritis

Recruiting

• Conditions: arthritis; rheumatoid arthritis; 10003816; 10023213

• Registration Number: NL-OMON55559
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

- 18 years or older
- diagnosis of peripheral arthritis
- active (drug resistant) inflammation of at least a (therapy resistant) knee
or ankle joint.

Exclusion Criteria

patients unable to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- to investigate pathogenic mechanisms in synovial tissue<br /><br>- to investigate these changes in the synovial tissue in relationship to the<br /><br>duration and different stages of inflammatory joint diseases<br /><br>- to investigate the relationship between these changes in the synovial tissue<br /><br>with changes in systemic immunity in different stages and forms of inflammatory<br /><br>joint diseases<br /><br>- to identify new therapeutic targets in the synovial tissue<br /><br>- to identify new diagnostic and prognostic markers in synovial tissue. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.A.</p><br>