Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Time to Exhaustion
Study Overview
Brief Summary
The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •BMI ≥ 30 kg/m2
- •Able to perform exercise testing on a cycle ergometer
Exclusion Criteria
- •Currently taking medications know to affect cardiovascular or respiratory function
- •Currently supplementing with an antioxidant compound
- •Current smoker
- •Currently taking antibiotics
- •Not willing to abstain from mouthwash use
- •Currently participating in regular physical activity
Arms & Interventions
Beetroot Juice
Intervention: Beetroot Juice (Dietary Supplement)
Beetroot Juice no Nitrate
Intervention: Beetroot Juice no Nitrate (Dietary Supplement)
Control
Sodium Nitrate
Intervention: Sodium Nitrate (Dietary Supplement)
Outcomes
Primary Outcomes
Time to Exhaustion
Time Frame: A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit.
Secondary Outcomes
No secondary outcomes reported
Investigators
Gordon Fisher
Associate Professor
University of Alabama at Birmingham