Clinical Features and Risk Factors of Craniopharyngioma With Tumoral Hemorrhage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 185
- 主要终点
- craniopharyngioma with tumoral hemorrhage
研究概览
简要总结
Clinical data of 185 consecutive patients receiving resective operation with a pathological diagnosis of craniopharyngioma in our hospital between January 2013 and February 2021 were collected. Among these patients, 18 of them were recognized as craniopharyngioma with tumoral hemorrhage during the operation.
详细描述
For each case, age, gender, smoking status, alcohol intake, past history, symptoms, blood pressure, blood cell count, blood biochemical tests, coagulation tests, hormone tests, radiological results, surgical treatment and the outcome at discharge were collected. The first test result after admission and before the operation was taken for the items of blood tests with multiple times in the analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •receive resective operation with a pathological diagnosis of craniopharyngioma in our hospital
- •enter our hospital between January 2013 and February 2021
排除标准
- •have a non-craniopharyngioma or unverified pathological diagnosis at discharge
- •have received surgical or radiological treatment on the sellar region
- •receive treatment of coagulation modulation, immunosuppressive agents or chemotherapeutic drugs
- •combine with other clinical emergencies including acute myocardial infarction, cerebral stroke, trauma and sepsis at admission
- •have been diagnosed with other tumors, hematological diseases, autoimmune diseases, liver failure or renal failure
结局指标
主要结局
craniopharyngioma with tumoral hemorrhage
时间窗: during the operation
Current study is a case-control study whose primary outcome is tumoral hemorrhage observed during the operation, which devided the craniopharyngioma patients into hemorrhage group and non-hemorrhage group.
次要结局
未报告次要终点