Study of Rotatory Vestibular Tests in Major Depression Patients and Healthy Control Subjects.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 主要终点
- Vestibular Activity
研究概览
简要总结
This study evaluates the vestibular activity in major depression patients and healthy controls using the rotatory test and electronystagmography.
详细描述
Previous studies showed abnormal vestibular activity in major depression patients using caloric vestibular tests. The present study investigates the vestibular response to vestibular rotatory tests in major depression subjects and healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •male and females adults (18 years or older)
- •met the Diagnosing and Statistical Manual of Mental Disorders (DSM-IV-R, American Psychiatric Association, 2000) criterion.
- •had a score of 12 or more in the Hamilton Rating Scale, 21 items for Depression.
- •with or without actual pharmacological treatment, except benzodiazepines that were suspended 24 hours before the rotary test when corresponding.
排除标准
- •pregnant women
- •neurologic disorders.
结局指标
主要结局
Vestibular Activity
时间窗: Vestibular rotatory test for each participant is about 50- 60 minutes. One rotatory test per participant.
The primary outcome corresponds to the vestibular activity. The vestibular stimulation provided by the rotatory chair is sensed by the inner ear´s vestibular receptors and generates reflex ocular movements(Vestibulo Ocular Reflex) registrated by electronystagmography. The main outcome corresponds to the asymmetry of the vestibular activity between both ears.
次要结局
未报告次要终点