A study to compare the efficacy of oral Curcuma longa in pulmonary tuberculosis patients
Phase 3
Not yet recruiting
- Conditions
- Health Condition 1: A150- Tuberculosis of lung
- Registration Number
- CTRI/2023/12/060532
- Lead Sponsor
- Jawarhalal Institute of Post Graduate Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Newly diagnosed smear positive drug sensitive pulmonary tuberculosis patients who have at least one sputum smear samples positive for tubercle bacilli (at least 1+) by auramine rhodamine staining- Patients willing to come for regular followup
Exclusion Criteria
-Patient with HIV
-Patients diagnosed with Chronic Kidney disease and Chronic liver disease requiring dose modifications.
-Pregnant and lactating women.
-Newly diagnosed tuberculosis patients with respiratory failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the proportion of patients achieving sputum smear conversion at the end of 1 month between oral Curcuma longa as an add on therapy to standard anti tuberculosis treatment and placebo with standard anti tuberculosis treatment in newly diagnosed drug sensitive pulmonary tuberculosis patientsTimepoint: 0, 1 month
- Secondary Outcome Measures
Name Time Method to compare adverse eventsTimepoint: 0, 1 month, 2 months, 6 months;to compare the change in inflammatory markersTimepoint: 0, 1 month;to compare treatment cureTimepoint: 0, 6 months