Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery

Not Applicable

Recruiting

• Conditions: Obese Patients With Bariatric Surgery; Lung Ultrasound Score

• Registration Number: NCT06950112
• Lead Sponsor: Mahmoud Gamal Ahmed Arakeeb

Brief Summary

this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score

Detailed Description

Not available

Study Timeline

• Study Start: 2024-12-01
• Study First Submitted: 2025-03-23
• Status Verified: 2025-04
• Study First Submitted QC: 2025-04-22
• Last Update Submitted: 2025-04-22
• Study First Posted: 2025-04-29
• Last Update Posted: 2025-04-29
• Primary Completion: 2025-12-01
• Study Completion: 2026-11-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. patients who have a BMI 30-40 kg/m2
2. American Society of Anesthesiologists (ASA) physical status II or III
3. patients aged between 18 and 60 years,
4. patients scheduled to undergo laparoscopic bariatric surgeries.

Exclusion Criteria

1. patients' refusal to participate in the study,
2. previous history of thoracic surgery,
3. Patients with a history of chest disease (COPD, emphysema, or pneumothorax),
4. Patients with abnormal pre-operative chest radiographs, such as pneumonia and pleural effusion,
5. Patients with right-side heart failure or impending failure,
6. Patients with known hypovolemia, and Patients with increased intracranial pressure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The change in lung ultrasound score	Periprocedural	The primary outcome will be the change in Lung Ultra Sound Score between 0 and 3 (0 = normal A lines, 1 = multiple separated B lines, 2 = coalescing B lines or light beam, 3 = consolidation) from the base line.

Secondary Outcome Measures

Name	Time	Method
Hemodynamic parameter as Heart rate	Periprocedural
End-tidal carbon dioxide (ETCO2)	Periprocedural
Peak airway pressure (Ppeak)	Periprocedural
Incidence of early postoperative pulmonary complications	At the end of the surgery up to 24 hours after surgery
Lung compliance	Periprocedural	Lung compliance is a measure of the expansion of the lung.
Hemodynamic parameter as oxygen saturation	Periprocedural
Hemodynamic parameter as Mean arterial blood pressure	Periprocedural
Plateau Pressure (Pplat)	Periprocedural
Length of post anesthesia care unit "PACU" stay.	At the end of the surgery up to 2 hours after surgery

Trial Locations

Locations (1)

Tanta university; 🇪🇬 Tanta, El gharbia, Egypt