Protective effect of N-acetylcysteine on INH-induced hepatotoxicity in patients with latent TB.

Phase 3

Recruiting

• Conditions: atent tuberculosis.; Latent tuberculosis; Z22.7

• Registration Number: IRCT20200328046886N4
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Patients diagnosed with latent tuberculosis using tuberculin skin test or IGRA.

Exclusion Criteria

Liver disease
Active tuberculosis
hepatitis
Pregnansy
Lactating
Alcoholism
Sensitivity to NAC

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Age. Timepoint: The beginning of the study. Method of measurement: questionnaire.;Sex. Timepoint: The beginning of the study. Method of measurement: questionnaire.;AST. Timepoint: The beginning ,first ,second,forth ,sixth, eighth weeks of the study. Method of measurement: Labrotory.;ALT. Timepoint: The beginning ,first ,second,forth ,sixth, eighth weeks of the study. Method of measurement: Labrotory.;Drug side effects. Timepoint: Start until the end of the study. Method of measurement: questionnaire.;ALP. Timepoint: The beginning and end of the study. Method of measurement: Labratory.;Bilirubin total. Timepoint: The beginning and end of the study. Method of measurement: Labratory.