KCT0002893
Recruiting
未知
The Preventive Coronary Intervention on Stenosis With Functionally Insignificant Vulnerable Plaque
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Asan Medical Center
- Enrollment
- 1600
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 19 years or older
- •Symptomatic or asymptomatic coronary artery disease patients
- •Patients having at least one significant stenosis (diameter stenosis \> 50%) with FFR \>0\.80 and meeting two of the following:
- •MLA(minimal luminal area)\<4mm2
- •plaque burden\>70%
- •Lipid\-rich plaque on NIRS(Intracoronary Near\-Infrared Spectroscopy) (defined as maxLCBI4mm\>315\)
- •TCFA(thin\-cap fibroatheroma) defined by OCT(fibrous cap thickness\<65µm and arc\>90°) or VH\-IVUS\=10% confluent NC with\>30° abutting to the lumen in 3 consecutive slices)
- •2 target vulnerable lesions
- •Eligible for percutaneous coronary intervention with Absorb Bioresorbable Vascular Scaffold or Everolimus Eluting Stent
- •Willing and able to provide informed written consent
Exclusion Criteria
- •Patients in whom the preferred treatment is CABG(Coronary artery bypass grafting)
- •Stented lesion
- •Bypass graft lesion
- •The patients who have more than or equal to 3 target lesions
- •2 target lesions in the same coronary territory
- •Heavily calcified or angulated lesion
- •Bifurcation lesion requiring 2 stenting technique
- •Contraindication to or planned discontinuation of dual antiplatelet therapy within 1 year
- •Life expectancy less than 2 years
- •Planned cardiac surgery or planned major non cardiac surgery
Outcomes
Primary Outcomes
Not specified
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