Effect of treatment with growth hormone in infertility”
Phase 3
- Conditions
- poor ovarian response.Female infertility associated with anovulation
- Registration Number
- IRCT20140818018842N14
- Lead Sponsor
- Deputy of Research and Technology, Tehran University of Medical Sciences.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 105
Inclusion Criteria
Sign the informed consent form
Patients with poor ovarian response based on criteria provided by the Union embryology and infertility Europe 2011.
Strong history of poor ovarian response (Having a maximum of three ovum after inducing ovulation protocols)
Low score ovarian reserve (AFC less than 7, AMH less than 0.5-1.1 ng/ml)
Exclusion Criteria
Women with high levels of FSH (more than 20 IU/L)
Women with a history of infertility due to known non poor ovarian resonce
Women with diabetes (type I or II)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The follicle number obtained in the ART cycle. Timepoint: Before starting treatment, on day eighth of a cycle, 36 hours after injecting HCG. Method of measurement: Trans vaginal ultrasonography.
- Secondary Outcome Measures
Name Time Method The number of metaphase II follicles achieved in the ART cycle. Timepoint: According embryologist report at ovum puncture. Method of measurement: Count of meta-phase II follicles in embryologist ward by microscopic observation.;The number of quality embryos obtained from the ART cycle. Timepoint: Third and fifth day after fertilization in the laboratory. Method of measurement: Report embryologists based grading A, B, C.;The number of positive pregnancy test. Timepoint: 14 days after embryo transfer. Method of measurement: BHCG over than 40 IU.;Successful clinical pregnancy. Timepoint: 6 to 8 weeks after embryo transfer. Method of measurement: Fetal Heart in Transvaginal ultrasonography.