TCTR20200805006招募中3 期
Spironolactone with Fixed-dose combination adapalene 0.1%/benzoyl peroxide 2.5% (A/BPO) compared to Doxycycline with Fixed-dose combination adapalene 0.1%/benzoyl peroxide 2.5% (A/BPO) for moderate to severe acne vulgaris in female patients
Ratchadaphiseksomphot Endowment Fund0 个研究点目标入组 80 人开始时间: 2020年8月5日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 45 Years（—）
- 性别
- Female
入选标准
- •1. Female patients 18-45 years old
- •2. Moderate to severe acne vulgaris
- •3. Did not use Topical retinoid, Benzoyl peroxide, Azelaic acid, or Salicylic acid within 1 month
- •4. Did not use Oral antibiotics (Doxycycline, Tetracycline, Minocycline), Oral retinoid, Antiandrogen, or Oral contraceptive pills within 3 months
- •5. Regular cycle (Interval 21-35 days)
- •6. Good compliance (Can visit every follow up)
- •7. Sign consent form
排除标准
- •1. Immunodeficiency (According to history taking and medical records) HIV patients, AIDS
- •2. Gynecologic conditions (According to history taking and medical records) Endometriosis, Polycystic ovarian syndrome, Ovarian cyst, Gynecologic cancer
- •3. Pregnant and lactating women
- •4. Allergy to Doxycycline, Spironolactone, or Epiduo®
- •5. Chronic kidney disease (Creatinine at the first day of inclusion > 1.4)
- •6. Serum potassium at the first day of inclusion > 5
- •7. Systolic blood pressure < 90, or Diastolic blood pressure < 60
研究者
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