Multisensory Training in PD

Not Applicable

• Conditions: Parkinson Disease
• Interventions: Other: Conventional training; Other: Multisensory training

• Registration Number: NCT05027555
• Lead Sponsor: National Yang Ming Chiao Tung University

Brief Summary

People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-08
• Study First Submitted: 2021-08-21
• Study First Submitted QC: 2021-08-26
• Last Update Submitted: 2021-08-26
• Study First Posted: 2021-08-30
• Last Update Posted: 2021-08-30
• Study Start: 2021-09-01
• Primary Completion: 2022-12-31
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Idiopathic PD
• Hoehn and Yahr stage I to III
• Age 60~80 y/o
• Mini-Mental State Examination (MMSE) ≥24
• Ability to ambulate independently (with or without walking aid)

Exclusion Criteria

• Affecting the peripheral vestibular system
• Medical condition that substantially influenced their gait and balance performance
• People had joined any rehabilitation past 1 month

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional training group.	Conventional training	The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks
Multisensory training group	Multisensory training	The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks

Primary Outcome Measures

Name	Time	Method
Gait variability	Change from baseline at 6 weeks	Using GAITRite system to measure coefficient of variation

Secondary Outcome Measures

Name	Time	Method
Sensory organization test	Change from baseline at 6 weeks	Using NeuroCom Smart Balance Master
Gait performance	Change from baseline at 6 weeks	Using the GAITRite system to evaluate saptiotemporal parameters
Timed up and go test	Change from baseline at 6 weeks	To evaluate functional mobility
Dynamic Gait Index	Change from baseline at 6 weeks	To evaluate functional mobility