NCT07747194Enrolling By Invitation不适用
Clinical Study and Mechanism Exploration of Acupuncture at Neiguan (PC6) for Preventing Nausea and Vomiting in Patients Undergoing Hematopoietic Stem Cell Transplantation
Xiao Wang1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年7月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Incidence and severity of nausea and vomiting during the conditioning regimen for hematopoietic stem cell transplantation
研究概览
简要总结
This study is testing whether acupuncture at a point on the wrist called "Neiguan" can help reduce nausea and vomiting in patients undergoing stem cell transplantation. Participants will receive either real acupuncture or standard care. We hope to find a safe way to improve comfort during cancer treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-65 years, either sex. Patients scheduled to receive a conditioning (preparative) regimen for hematopoietic stem cell transplantation (HSCT).
- •Life expectancy ≥ 3 months. Eastern Cooperative Oncology Group (ECOG) performance status of 0-
- •Women of childbearing potential must have a negative pregnancy test (serum or urine) within 7 days prior to enrollment.
- •Voluntary participation with signed informed consent.
排除标准
- •Received chemotherapy with highly emetogenic agents within 14 days prior to enrollment.
- •Received radiotherapy within 7 days prior to enrollment, or planned radiotherapy during the study period.
- •Known hypersensitivity to any study drug or its excipients. Complicated with gastrointestinal obstruction, brain metastasis with symptoms of increased intracranial pressure, or any other condition that may cause and/or exacerbate nausea and vomiting.
- •Active infection. Unable to take oral medications. Use of any anti-emetic medication (including corticosteroids) within 48 hours or 5 half-lives of the drug (whichever is longer) prior to enrollment.
- •Any episode of nausea, vomiting, or retching within 24 hours prior to the first administration.
- •Severe psychiatric illness or cognitive impairment that precludes understanding, reading, and completing patient diaries.
- •Any other condition that the investigator deems would make the patient unsuitable for participation in this study.
研究组 & 干预措施
Standard Care
Active Comparator
干预措施: Conventional care (Drug)
Acupuncture at Neiguan
Experimental
干预措施: Acupuncture (Procedure)
结局指标
主要结局
Incidence and severity of nausea and vomiting during the conditioning regimen for hematopoietic stem cell transplantation
时间窗: Throughout the conditioning period (approximately 3-7 days)
次要结局
- Nutritional status assessed by serum albumin and prealbumin levels(Baseline (pre-conditioning), Day 7, Day14, and Day 28 of conditioning, and Day 30 post-transplant)
研究者
Xiao Wang
Attending Physician
The General Hospital of Western Theater Command
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Effects of Different Acupuncture Techniques on the Success Rate in Patients With Recurrent Implantation FailureImplantation FailureNCT07669623Cui Hong Zheng312
招募中
4 期
Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep Disorders in ChinaAnxiety DepressionSleepNCT07552246Duke Kunshan University180
尚未招募
不适用
Evaluating whether Master Tung Acupuncture can reduce pain and stiffness in Frozen ShoulderCTRI/2025/12/098680Dr Kalaiselvan G90
尚未招募
不适用
Acupuncture treatment for improving cognitive function among postmenopausal womenCTRI/2025/12/099848Dr Fahumidha sinaz S70
已完成
不适用
Evaluation of the Effect of Acupuncture on Objective Outcomes in Patients With Chronic Neck DiscomfortNeck Pain ChronicNCT07681349Hualien Tzu Chi General Hospital50