The Efficacy of Severe Whitening and Delayed Fading in Acetic Acid-enhanced Endoscopy for Diagnosing Gastric Intestinal Metaplasia
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- accuracy of "severe whitening" for diagnosing gastric intestinal metaplasia
研究概览
简要总结
Investigators found that the degree and the duration of aceto-whitening differed between gastric intestinal metaplasia(GIM) and the surrounding normal mucosa: the area of GIM showed a severe degree of aceto whiteness and the whitening continued longer than the surrounding normal mucosa, which investigators called "severe whitening" and "delayed fading", and investigators realized that GIM could possibly be diagnosed by using these differences.The aim of this prospective study was to investigate the efficacy of "severe whitening" and "delayed fading" for diagnosing GIM.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •long-lasting upper gastrointestinal symptoms (>15 years)
- •atrophic gastritis or GIM identified at surveillance endoscopy
排除标准
- •presence of advanced adenocarcinoma in the stomach
- •presence of acute gastrointestinal bleeding
- •presence of coagulopathy, uncontrolled impaired renal or liver disease
- •presence of pregnancy or lactation
- •presence of allergy to acetic acid
- •age younger than 18 years or older than 80 years
- •inability to provide written informed consent.
研究组 & 干预措施
acetic acid-enhanced endoscopy
Acetic acid-enhanced endoscopy combines conventional endoscopy with the instillation of acetic acid.
干预措施: acetic acid-enhanced endoscopy (Procedure)
acetic acid-enhanced endoscopy
Acetic acid-enhanced endoscopy combines conventional endoscopy with the instillation of acetic acid.
干预措施: Acetic Acid (Drug)
acetic acid-enhanced endoscopy
Acetic acid-enhanced endoscopy combines conventional endoscopy with the instillation of acetic acid.
干预措施: endoscope (Device)
结局指标
主要结局
accuracy of "severe whitening" for diagnosing gastric intestinal metaplasia
时间窗: 6 months
accuracy of "delayed fading" for diagnosing gastric intestinal metaplasia
时间窗: 6 months
次要结局
未报告次要终点
研究者
Xiuli Zuo
director of Qilu Hospital
Shandong University