Acute Effect of Topical Menthol on Neck Pain
- Conditions
- Musculoskeletal Disorders
- Interventions
- Other: PlaceboOther: Biofreeze
- Registration Number
- NCT01542827
- Lead Sponsor
- National Research Centre for the Working Environment, Denmark
- Brief Summary
Topical menthol gels are classified 'topical analgesics' and are used to relieve aching and tenderness of muscles and joints. However, double-blind randomized controlled trials are lacking. Here the investigators examine - in a double-blind randomized controlled cross-over trial - the acute effect of topical menthol (Biofreeze) and placebo (gel with a menthol scent) on neck pain.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 20
- more than 30 days with neck pain during the last year
- frequent pain or discomfort, defined as at least 3 days per week
- pain intensity at least 4 on a scale of 0-10
- working at least 30 hours per week
- blood pressure above 160/100 mmHg
- pregnancy
- life-threatening disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Placebo Placebo Topical gel containing a menthol scent, but no active menthol Biofreeze Biofreeze Biofreeze topical gel containing 3.5% menthol
- Primary Outcome Measures
Name Time Method Neck pain intensity (scale 0-10) before and 20 min after application the participant rates pain intensity on a scale from 0-10 immediately before, and 0, 10, 20, 40 and 60 minutes after application of the gel. The primary efficacy endpoint is at 20 min
- Secondary Outcome Measures
Name Time Method Pressure pain threshold (PPT) before and 20 min after application pressure pain threshold of the upper trapezius muscle is measured by a handheld algometer immediately before, and 0, 10, 20, 40 and 60 minutes after application of the gel.
Trial Locations
- Locations (1)
National Research Centre for the Working Environment
🇩🇰Copenhagen, Denmark