Metformin as an adjunct therapy in type 1 diabetes

Not Applicable

• Conditions: Diabetes 1.; Insulin-dependent diabetes mellitus

• Registration Number: IRCT2016120110988N5
• Lead Sponsor: Vice Chancellor for research of Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

Inclusion criteria included Age >10; Duration of type 1 diabetes (T1DM) >1 year; Insulin dosage>1u/kg/d; HbA1C>8% (relative control). Exclusion criteria included Nephropathies; Retinopathies; Occurrence of diabetic ketoacidocis (DKA) more than twice per year; Acute hypoglycemia with loss of consciousness to a level necessitating help more than twice per year; Liver diseases or other underlying diseases

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HbA1C. Timepoint: Before the intervention and repeated with 3 months intervals till the end of study (12 months). Method of measurement: Laboratory.;Serum creatinine. Timepoint: Before the intervention and at the end of the study (12 months). Method of measurement: Laboratory.;Serum lactate. Timepoint: Before the intervention and at the end of the study (12 months). Method of measurement: Laboratory.;Serum lipids. Timepoint: Before the intervention and at the end of the study (12 months). Method of measurement: Laboratory.