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euroimaging of the effects of Deep Brain Stimulation in patients with Obsessive Compulsive Disorder.

Conditions
Obsessive Compulsive Disorder (OCD)
compulsive behaviour
Registration Number
NL-OMON31543
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
16
Inclusion Criteria

- Subjects have signed informed consent.
- Neurostimulator has been implanted according to METC protocol number 04/113-E
- Fulfilling in and exclusion criteria according METC protocol number 04/113-E
- No use of psychotropic medication 4 weeks before the scan procedure.

Exclusion Criteria

- Participation in a SPECT of PET study in the year prior to this study.
- Radiological workers
- Use of drugs
- Pregnancy
- Use of tabacco, alcohol, coffee, tea and chocolate 24 hours before the scanning
procedure, since brain metabolism may be influenced by these products.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>fMRI will be used to determine alterations in cerebral perfusion<br /><br>IBZM SPECT will be used to determine alteration in D2 receptor binding.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Not applicable.</p><br>
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