ovel brain biomarkers of performance impairment in good sleepers

Not Applicable

Recruiting

• Conditions: ormal brain and nervous system functioning; Normal brain and nervous system functioning; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12615001224516
• Lead Sponsor: Cooperative Research Centre (CRC) for Alertness, Safety and Productivity

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Age 25-65 years
Weight <150kg
Ability to read and speak English
Ability to perform neurobehavioural tests

Exclusion Criteria

PSG confirmed sleep disorders (e.g. OSA)
History of head injury or psychiatric/neurological disorders: clinical
depression, epilepsy, mania or psychosis, stroke
Currently using CNS active medications/drugs such as: anti-depressives, anti-psychotics, opiates, antihistamines

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Driving simulator (AusED) steering deviations<br>[-Time 1 (baseline - 3.5 hours awake) Midday<br>-Time 2 (20.5 hours awake)<br>-Time 3 (26.5 hours awake)];10 minute Psychomotor Vigilance Task - Reaction time[-Time 1 (baseline - 3.5 hours awake) Midday<br>-Time 2 (20.5 hours awake)<br>-Time 3 (26.5 hours awake)]