Renal Resistivity Index as a predictor of acute kidney injury recovery in patient in liver ICU: a prospective observational study

This is a prospective single arm observational study designed with 118 patients, of male and female genders, to investigate whether the Renal Resistive Index measured in a patient admitted to Liver ICU with acute kidney injury can predict the recovery of the same through the course of treatment.

The Renal Resistive Index or RRI is a value derived from the ultrasound guided imaging of the arteries supplying the kidneys. This value was found to be increased in patients with acute kidney injury with the levels reducing with the recovery of the kidney injury.

In this study, the RRI value will be measured at the time of admission to ICU and the same will be followed up on day 1 through 3 of treatment.

Other values and inputs such as the laboratory investigations of creatinine, volume status such as IVC measurement, Vti, biomarker levels such as NGAL will also be followed up during the course of treatment (Day 1 through 3).

Other details such as need for renal replacement therapy, mechanical ventilation, days of ICU and hospital stay, 30 and 90 day mortality will also be followed up.