A comparative study of Propofol and Sodium Thiopentone as an induction agents in Modified Electro Convulsive Therapy.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Duration of Seizure.
研究概览
简要总结
Modified Electroconvulsive Therapy (ECT) is widely used to treat severe psychiatric disorders like major depression, bipolar disorder, and schizophrenia.
Anesthesia is essential during ECT to ensure patient comfort and safety.
Among the anesthetic agents commonly used, Propofol and Thiopentone Sodium are popular due to their rapid onset and short duration of action, though they differ in clinical effects.
Propofol is known for faster recovery, antiemetic effects, and minimal ECT confusion. However, it often leads to shorter seizure durations, which may affect therapeutic efficacy.
On the other hand, Thiopentone provides longer seizure durations but may result in delayed recovery and greater hemodynamic fluctuations.
Given these contrasting profiles, selecting the appropriate induction agent becomes crucial for optimizing ECT outcomes.
This study aims to compare Propofol and Thiopentone Sodium with respect to seizure duration, hemodynamic stability, recovery time, and adverse effects in patients undergoing modified ECT.
By conducting a cross-sectional study, the project seeks to provide evidence-based guidance on which agent offers a better balance between safety, efficacy, and recovery in the ECT setting.
The results are expected to aid anesthesiologists in selecting the most suitable induction agent tailored to individual patient needs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA grade 1 and
- •Patients indicated for modified ECT.
- •Provided informed written consent.
排除标准
- •Allergy to any known drugs.
- •Pregnant orr lactating women.
- •Substance abuse history.
结局指标
主要结局
Duration of Seizure.
时间窗: After electical stimulus From first visible seizure movement to the cessation of tonic clonic activity.
次要结局
未报告次要终点
研究者
Dr Riddhiben Dahyabhai Patel
Gujrat Adani Institute Of Medical Science , G .K . General Hospital , Bhuj.
