Mechanistic and clinical effects of the regulation of inhibitory control networks via real-time fMRI neurofeedback in smokers
Not Applicable
Recruiting
- Conditions
- Smokers
- Registration Number
- DRKS00027056
- Lead Sponsor
- niversitätsklinikum der RWTH Aachen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Smoke more 10 cigarettes per day for at least 1 year
- Good German knowledge
Exclusion Criteria
- Severe psychiatric disease
- MR contraindications
- Pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in inhibitory control performance as measured by Stop Signal task before and after neurofeedback session, using repeated measure ANOVA with the factors ‘Group’ (neurofeedback experimental condition, neurofeedback sham condition) and ‘Time’ (Pre-neurofeedback, Post-neurofeedback)
- Secondary Outcome Measures
Name Time Method - Neurofeedback specific changes in functional connectivity of the target network<br>- Changes in nicotine consumption and impulsivity trait, measured by Fagerstrom Test for Nicotine Dependence (FTND), Barratt Impulsiveness Scale (BIS-11), and UPPS Impulsive Behavior Scale in initial and follow-up (4 weeks later) assessment<br>- Transient changes in resting-state connectivity, measured before and after neurofeedback session?